NCT00002601View on ClinicalTrials.gov

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma

PHASE2CompletedINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

September 30, 1994

Primary Completion Date

September 30, 2014

Study Completion Date

September 30, 2014

Conditions
Sarcoma
Interventions
BIOLOGICAL

filgrastim

5 ug/kg daily following stem cell reinfusion

DRUG

cisplatin

Course 2 - 100 mg/m2 at an infusion rate of 25 mg/hr

DRUG

doxorubicin hydrochloride

Course 1 - 150 mg/m2 by continuous intravenous infusion for 96 hours.

DRUG

ifosfamide

Course 1 - 14 gm/M2 by continuous intravenous infusion for 96 hours.

DRUG

melphalan

Course 2 - 75 mg/m2 infused at a rate of 5 mg/minute

PROCEDURE

peripheral blood stem cell transplantation

Administered on Day 0 following high-dose chemotherapy in both courses 1 and 2

Trial Locations (1)

91010-3000

Cancer Center and Beckman Research Institute, City of Hope, Duarte

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER