A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDS

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

Not specified

Conditions
Herpes SimplexHIV Infections
Interventions
DRUG

Cidofovir

Trial Locations (9)

21205

Johns Hopkins Hosp, Baltimore

27599

Univ of North Carolina Hosps, Chapel Hill

60612

Rush Presbyterian - Saint Luke's Med Ctr, Chicago

77004

Park Plaza Hosp, Houston

90033

Los Angeles County - USC Med Ctr, Los Angeles

94110

UCSF - San Francisco Gen Hosp, San Francisco

94115

Mount Zion Med Ctr / UCSF, San Francisco

98122

Univ of Washington / Viral Disease Clinic, Seattle

Unknown

Univ of British Columbia / Univ Hosp, Vancouver

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gilead Sciences

INDUSTRY

NCT00002116 - A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDS | Biotech Hunter | Biotech Hunter