A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDS

PHASE2CompletedINTERVENTIONAL
Enrollment

246

Participants

Timeline

Start Date

Not specified

Study Completion Date

January 31, 1999

Conditions
Mycobacterium Avium-intracellulare InfectionHIV Infections
Interventions
DRUG

Indinavir sulfate

DRUG

Ritonavir

DRUG

Ethambutol hydrochloride

DRUG

Clarithromycin

DRUG

Rifabutin

Trial Locations (34)

10003

Beth Israel Med. Ctr. (Mt. Sinai), New York

10016

NY Univ. HIV/AIDS CRS, New York

14260

SUNY - Buffalo, Erie County Medical Ctr., Buffalo

14642

Univ. of Rochester ACTG CRS, Rochester

19104

Hosp. of the Univ. of Pennsylvania CRS, Philadelphia

21287

Johns Hopkins Adult AIDS CRS, Baltimore

27514

Unc Aids Crs, Chapel Hill

30308

The Ponce de Leon Ctr. CRS, Atlanta

35294

Alabama Therapeutics CRS, Birmingham

43210

The Ohio State Univ. AIDS CRS, Columbus

45267

Univ. of Cincinnati CRS, Cincinnati

46202

Indiana Univ. School of Medicine, Infectious Disease Research Clinic, Indianapolis

Indiana Univ. School of Medicine, Wishard Memorial, Indianapolis

Methodist Hosp. of Indiana, Indianapolis

55415

Hennepin County Med. Ctr., Div. of Infectious Diseases, Minneapolis

55455

University of Minnesota, ACTU, Minneapolis

60611

Northwestern University CRS, Chicago

60612

Cook County Hosp. CORE Ctr., Chicago

Rush Univ. Med. Ctr. ACTG CRS, Chicago

60640

Weiss Memorial Hosp., Chicago

63110

Washington U CRS, St Louis

63112

St. Louis ConnectCare, Infectious Diseases Clinic, St Louis

80045

University of Colorado Hospital CRS, Aurora

90033

USC CRS, Los Angeles

90035

UCLA CARE Center CRS, Los Angeles

90502

Harbor-UCLA Med. Ctr. CRS, Torrance

92103

Ucsd, Avrc Crs, San Diego

94110

Ucsf Aids Crs, San Francisco

96813

Queens Med. Ctr., Honolulu

96816

Univ. of Hawaii at Manoa, Leahi Hosp., Honolulu

98104

University of Washington AIDS CRS, Seattle

02118

Bmc Actg Crs, Boston

02215

Beth Israel Deaconess - East Campus A0102 CRS, Boston

Unknown

Mbeya Med. Research Program, Mbeya Referral Hosp. CRS, Mbeya

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00001058 - A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDS | Biotech Hunter | Biotech Hunter