A Phase II, Comparative Study of Seroconversion of Single-Dose and Two-Dose Measles Vaccination in HIV-Infected and HIV-Uninfected Children: A Multicenter Trial of the Pediatric AIDS Clinical Trials Group

PHASE2CompletedINTERVENTIONAL
Enrollment

270

Participants

Timeline

Start Date

Not specified

Study Completion Date

August 31, 2001

Conditions
HIV InfectionsMeasles
Interventions
BIOLOGICAL

Attenuvax

Measles virus vaccine (attenuate)administered subcutaneously at a single dose of 0.5 mL at 6 months of age

BIOLOGICAL

M-M-R-II

Measles-Mumps-Rubella vaccine (attenuated)administered subcutaneously as a single dose of 0.5 mL at 12 months of age

Trial Locations (46)

10016

NYU Med. Ctr., Dept. of Medicine, New York

10029

Metropolitan Hosp. Ctr., New York

Metropolitan Hosp. NICHD CRS, New York

10032

Columbia IMPAACT CRS, New York

Incarnation Children's Ctr., New York

10037

Harlem Hosp. Ctr. NY NICHD CRS, New York

11021

North Shore-Long Island Jewish Health System, Dept. of Peds., Great Neck

11040

Schneider Children's Hosp., Div. of Infectious Diseases, New Hyde Park

12208

Children's Hospital at Albany Medical Center, Dept. of Peds., Albany

13210

SUNY Upstate Med. Univ., Dept. of Peds., Syracuse

20010

Children's National Med. Ctr., ACTU, Washington D.C.

20060

Howard Univ. Washington DC NICHD CRS, Washington D.C.

23507

Childrens Hosp. of the Kings Daughters, Norfolk

27710

DUMC Ped. CRS, Durham

30306

Emory Univ. School of Medicine, Dept. of Peds., Div. of Infectious Diseases, Atlanta

35233

UAB, Dept. of Ped., Div. of Infectious Diseases, Birmingham

48201

Children's Hospital of Michigan NICHD CRS, Detroit

60612

Cook County Hosp., Chicago

60614

Chicago Children's CRS, Chicago

90033

Usc La Nichd Crs, Los Angeles

90801

Long Beach Memorial Med. Ctr., Miller Children's Hosp., Long Beach

94609

Children's Hosp. & Research Ctr. Oakland, Ped. Clinical Research Ctr. & Research Lab., Oakland

Unknown

UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CRS, Los Angeles

UCSD Maternal, Child, and Adolescent HIV CRS, San Diego

Harbor - UCLA Med. Ctr. - Dept. of Peds., Div. of Infectious Diseases, Torrance

Univ. of Colorado Denver NICHD CRS, Aurora

Univ. of Florida Jacksonville NICHD CRS, Jacksonville

Univ. of Chicago - Dept. of Peds., Div. of Infectious Disease, Chicago

Univ. of Illinois College of Medicine at Chicago, Dept. of Peds., Chicago

Tulane/LSU Maternal/Child CRS, New Orleans

Johns Hopkins Hosp. & Health System - Dept. of Peds., Div. of Infectious Diseases, Baltimore

Univ. of Maryland Med. Ctr., Div. of Ped. Immunology & Rheumatology, Baltimore

HMS - Children's Hosp. Boston, Div. of Infectious Diseases, Boston

UMDNJ - Robert Wood Johnson, New Brunswick

NJ Med. School CRS, Newark

Strong Memorial Hospital Rochester NY NICHD CRS, Rochester

SUNY Stony Brook NICHD CRS, Stony Brook

The Children's Hosp. of Philadelphia IMPAACT CRS, Philadelphia

Med. Univ. of South Carolina, Div. of Ped. Infectious Diseases, Charleston

Texas Children's Hosp. CRS, Houston

UW School of Medicine - CHRMC, Seattle

Univ. Hosp. Ramón Ruiz Arnau, Dept. of Peds., Bayamón

San Juan City Hosp. PR NICHD CRS, San Juan

Univ. of Puerto Rico Ped. HIV/AIDS Research Program CRS, San Juan

06504

Yale Univ. School of Medicine - Dept. of Peds., Div. of Infectious Disease, New Haven

07503

St. Joseph's Hosp. & Med. Ctr. of New Jersey, Paterson

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00000815 - A Phase II, Comparative Study of Seroconversion of Single-Dose and Two-Dose Measles Vaccination in HIV-Infected and HIV-Uninfected Children: A Multicenter Trial of the Pediatric AIDS Clinical Trials Group | Biotech Hunter | Biotech Hunter