Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT)

PHASE3CompletedINTERVENTIONAL
Enrollment

61

Participants

Timeline

Start Date

May 31, 1997

Primary Completion Date

June 30, 2000

Study Completion Date

June 30, 2000

Conditions
Cytomegalovirus RetinitisHIV Infections
Interventions
DEVICE

Ganciclovir implant and oral ganciclovir

oral ganciclovir, 1 gm three times daily

DRUG

Cidofovir intravenous

intravenous, 5 mg/kg once weekly for two doses, followed by 5 mg/kg every other week

Trial Locations (19)

10016

Department of Ophthalmology, New York University Medical Center, New York

10021

Department of Ophthalmology, New York Hospital-Cornell Medical Center, New York

30322

The Emory Clinic, Emory University, Atlanta

33136

Bascom Palmer Eye Institute, University of Miami, Miami

60611

Department of Ophthalmology, Northwestern University, Chicago

70112

LSU Eye Center, Louisiana State University Medical Center, New Orleans

77030

Cullen Eye Institute, Baylor College of Medicine, Houston

90033

LAC/USC Medical Center, 5P21 Rand Schrader Clinic, Los Angeles

94143

Beckman Vision Center, University of California, San Francisco, San Francisco

92697-4375

Department of Ophthalmology, University of California, Irvine, Irvine

92093-0946

Shiley Eye Center Center, 0946, University of California, San Diego, La Jolla

90095-7003

Jules Stein Eye Institute, University of California, Los Angeles, Los Angeles

33612-4799

University of South Florida, MDC Box 21, Tampa

46202-2879

Division of Infectious Diseases, Indiana University, Indianapolis, Indianapolis

21287-9217

The Wilmer Ophthalmological Institute, The Johns Hopkins University School of Medicine, Baltimore

02114

Harvard/BCH AIDS Clinical Trials Unit, Massachusetts General Hospital, Boston

07103-2499

UMDNJ-New Jersey Medical School, Newark

10029-6574

Department of Ophthalmology, Mount Sinai School of Medicine, New York

27599-7030

University of North Carolina at Chapel Hill, Chapel Hill

All Listed Sponsors
lead

Johns Hopkins Bloomberg School of Public Health

OTHER