Peptide Drugs
Total Trials
43
As Lead Sponsor
38
As Collaborator
5
Total Enrollment
3,668
NCT00283361
ZP120 Add-on to Furosemide in Treatment of Acute or Sub-Acute Decompensated Heart Failure
Phase: Phase 2
Role: Lead Sponsor
Start: Jan 31, 2006
Completion: Dec 31, 2006
NCT00868660
Healthy Normal Single Ascending Dose and Crohn's Patient Multiple Ascending Dose
Phase: Phase 1
Start: Jan 31, 2009
Completion: Feb 28, 2010
NCT02201550
Study of Immune Cells in Obese Patients With Type 2 Diabetes Mellitus Treated With Liraglutide
Phase: N/A
Role: Collaborator
Start: Feb 28, 2013
Completion: Apr 30, 2014
NCT01977755
Phase 2 Clinical Proof-of-Concept Study of the Cardioprotective Properties of Danegaptide in ST Segment Elevation Myocardial Infarction
Start: Nov 30, 2013
Completion: Jun 8, 2016
NCT02367053
Single Ascending Doses of ZP4207 Administered in HV and in T1D to Evaluate Safety, Tolerability PKs and PDs of ZP4207 Compared to a Comparator
Start: Dec 31, 2014
Completion: Apr 30, 2015
NCT02390141
Multiple Ascending Doses of ZP4207 Administered to HV to Evaluate the Safety, Tolerability, PKs and PDs of ZP4207
Start: Apr 30, 2015
Completion: Aug 31, 2015
NCT02660008
Single Doses of ZP4207 Adm. sc to Hypoglycemic TD1 pt. to Describe the PK and PD of ZP4207 as Comp. to Marketed Glucagon
Start: Jan 31, 2016
Completion: Jun 30, 2016
NCT02690025
A Phase 2 Trial Testing ZP1848 in Patients With SBS
Start: Feb 29, 2016
Completion: May 31, 2017
NCT02971228
Feasibility Trial Testing the Bionic Pancreas With ZP4207
Start: Nov 30, 2016
Completion: Jun 7, 2017
NCT02916251
ZP4207(Dasiglucagon) Administered to T1D Patients to Assess the PK and PD Compared to Marketed Glucagon
Start: Dec 1, 2016
Completion: Apr 5, 2017
NCT03216226
A Trial to Evaluate the Immunogenicity of Dasiglucagon and GlucaGen in Patients With Type 1 Diabetes Mellitus
Phase: Phase 3
Start: Jun 28, 2017
Completion: Feb 13, 2018
NCT03279302
Trial to Evaluate the PK Profile of Glepaglutide (ZP1848) After a Single IV and After Multiple SC Injections in Healthy Subjects
Start: Sep 4, 2017
Completion: Dec 18, 2017
NCT03526289
GIP/GLP-1 Co-Activity in Subjects With Overweight and Type 2 Diabetes: Lowering of Food Intake
Start: Nov 8, 2017
Completion: Oct 24, 2018
NCT03378635
A Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Type 1 Diabetes Subjects
Start: Dec 7, 2017
Completion: May 25, 2018
NCT03667053
Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in T1DM Children
Start: Sep 28, 2018
Completion: Jun 28, 2019
NCT03690206
Efficacy And Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome (SBS)
Start: Oct 4, 2018
Completion: Jul 26, 2022
NCT03688711
Trial to Confirm the Clinical Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Subjects With T1DM
Start: Nov 1, 2018
Completion: Mar 11, 2019
NCT03735225
Evaluation of the Safety, Tolerability and Bioavailability of Dasiglucagon Following Subcutaneous (SC) Compared to IV Administration
Start: Nov 7, 2018
Completion: Jun 24, 2019
NCT03777176
A Two-Period Open-label Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism
Start: Feb 7, 2019
Completion: Oct 5, 2020
NCT03895697
A Trial to Compare the Efficacy and Safety of 2 Different Batches of Subcutaneous Dasiglucagon in Patients With T1DM
Start: Mar 26, 2019
Completion: Jul 30, 2019
NCT03941236
Extension Trial Evaluating the Long-term Safety and Efficacy of Dasiglucagon in Children With Congenital Hyperinsulinism
Start: May 1, 2019
Completion: Dec 31, 2026
NCT03905707
Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS
Start: May 7, 2019
Completion: Oct 31, 2026
NCT03840278
The Bihormonal iLet Bionic Pancreas Feasibility Study
Phase: Phase 2/3
Start: May 15, 2019
Completion: Jul 3, 2019
NCT03994549
A Single Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570
Phase: Early Phase 1
Start: Jun 14, 2019
Completion: Nov 2, 2020
NCT04178447
Pharmacokinetic Profile of Glepaglutide After a Single Injection in Subjects With Varying Degrees of Renal Function
Start: Dec 10, 2019
Completion: Jul 14, 2020
NCT04318743
A Bridging Trial to Compare the PK Profile When Glepaglutide is Administered Via Vial/Syringe Versus Autoinjector.
Start: Mar 4, 2020
Completion: Jun 10, 2021
NCT04172441
Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism
Start: Jun 19, 2020
Completion: Mar 7, 2022
NCT04612517
A Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570
Start: Oct 26, 2020
Completion: Aug 30, 2021
NCT04881825
Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS - Extension Trial
Start: Jun 16, 2021
Completion: Apr 30, 2025
NCT04991311
The Long-term Effect on Intestinal Absorption and Safety of Treatment With Glepaglutide in Patients With Short Bowel Syndrome
Start: Aug 10, 2021
Completion: Sep 5, 2023
NCT04836273
Treatment of Post-bariatric Hypoglycaemia
Start: Aug 20, 2021
Completion: Dec 15, 2022
NCT05096598
A First-in-human Study Looking at the Safety of ZP8396 and How it Works in the Body of Healthy Trial Participants
Start: Oct 19, 2021
Completion: Jan 12, 2023
NCT05613387
A Research Study Looking at the Safety of Multiple Doses of ZP8396 and How it Works in the Body of Healthy Participants
Start: Nov 7, 2022
Completion: Jun 13, 2024
NCT04824872
Efficacy and Safety of Dasiglucagon for Treatment of Post-bariatric Hypoglycemia in Roux-en-Y Gastric Bypass (RYGB) Operated Adults
Start: Feb 28, 2023
Completion: Feb 28, 2023
NCT05788601
Dapiglutide for the Treatment of Obesity
Start: Apr 27, 2023
Completion: Aug 15, 2025
NCT05378672
A Study to Inv. Safety, Efficacy & PD of Dasiglucagon as Hypoglycemia Rescue Therapy in Children <6 Years With T1D
Start: May 9, 2023
Completion: Dec 3, 2024
NCT06000891
A Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570
Start: Sep 15, 2023
Completion: Mar 21, 2025
NCT06682975
A Research Study Looking at the Safety of Single Doses of ZP9830 and How it Works in the Body of Healthy Participants
Start: Nov 12, 2024
Completion: Dec 31, 2025
NCT06662539
Once-weekly Petrelintide Versus Placebo for Obesity or Overweight With Co-morbidities
Start: Dec 9, 2024
Completion: Mar 16, 2026
NCT06758583
A Trial Comparing Pharmacokinetics, Safety and Tolerability of Two Subcutaneous Concentrations of Dapiglutide
Start: Dec 23, 2024
Completion: Apr 25, 2025
NCT07076030
Pharmacokinetics of Petrelintide Following Administration to Participants With Impaired Renal Function
Start: Apr 15, 2025
NCT06926842
Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes (ZUPREME 2)
Start: Apr 22, 2025
Completion: Jun 4, 2026
NCT07197944
Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS
Start: Oct 23, 2025
Completion: Feb 28, 2032
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