Treatments for Rare or Neglected Diseases
Total Trials
10
As Lead Sponsor
8
As Collaborator
2
Total Enrollment
5,110
NCT02516579
European Sickle Cell Disease Cohort - Hydroxyurea
Phase: N/A
Role: Lead Sponsor
Start: Jan 31, 2009
Completion: Mar 20, 2019
NCT02522104
Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH)
Phase: Phase 4
Start: Sep 3, 2015
Completion: Nov 28, 2016
NCT02957760
Prevention of Retinal Non-perfusion in Central Retinal Vein Occlusion by Hydroxycarbamide Treatment.
Phase: Phase 2
Role: Collaborator
Start: Dec 31, 2015
Completion: Dec 31, 2017
NCT03032055
Validation of a Predictive Score of Acute Chest Syndrome
Start: Jan 1, 2016
Completion: Dec 31, 2023
NCT02721472
Plasma DNA and Vascular Remodelling in Patients With Sickle Cell Disease
Start: May 17, 2016
Completion: Nov 14, 2019
NCT03806452
SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial)
Start: May 28, 2019
Completion: May 30, 2024
NCT04707235
ESCORT-HU Extension: European Sickle Cell Disease Cohort - Hydroxyurea - Extension Study
Start: Aug 21, 2020
Completion: Aug 21, 2025
NCT05025072
A Bioequivalence Study to Compare the Pharmacokinetics of Two Formulations of Siklos® in Healthy Volunteers
Phase: Phase 1
Start: Aug 22, 2021
Completion: Sep 29, 2021
NCT05470270
Acceptability of a New Paediatric Formulation of Hydroxycarbamide in Children With Sickle Cell Disease.
Start: Jul 8, 2022
Completion: Oct 28, 2022
NCT06578507
Pharmacokinetics, Efficacy and Safety of Twice Daily Dosing Regimen of Hydroxycarbamide Dispersible Tablets in Children With Sickle Cell Disease
Start: Jan 21, 2025
Completion: Feb 28, 2027
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