About
Treatments for diseases affecting the hypothalamic-pituitary-adrenal (HPA) axis
Areas of Focus
Categories
Small Molecule PharmaceuticalBiotech
Team (11)
Bali Muralidhar, Ph.D.
Bali Muralidhar, Ph.D.
Spruce Biosciences
team_member
Camilla V. Simpson, M.Sc.
Camilla V. Simpson, M.Sc.
Spruce Biosciences
team_member
Dan Spiegelman, M.B.A.
Dan Spiegelman, M.B.A.
Spruce Biosciences
team_member
Dasharatha Reddy, Ph.D.
Dasharatha Reddy, Ph.D.
Spruce Biosciences
team_member
Javier Szwarcberg, M.D., M.P.H.
Javier Szwarcberg, M.D., M.P.H.
Spruce Biosciences
team_member
Kirk Ways, M.D., Ph.D.
Kirk Ways, M.D., Ph.D.
Spruce Biosciences
team_member
Clinical Trials (6)
View allTotal Trials
6
As Lead Sponsor
6
As Collaborator
0
Total Enrollment
323
By Phase
PHASE2: 6
By Status
TERMINATED: 4COMPLETED: 2
Clinical Trials Pipeline6 trials
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Phase 1/2
Phase 2/3
N/A
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Today
Hover over trial bars to see details
Recent Trials
NCT05370521Lead Sponsor
A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens
PHASE2Terminated
27 participants
Started: May 15, 2022 · Completed: Aug 31, 2023
NCT05128942Lead Sponsor
A Phase 2 Study to Evaluate the Safety, Efficacy and PK of Tildacerfont in Children with CAH
PHASE2Terminated
65 participants
Started: Dec 10, 2021 · Completed: Jan 31, 2025
NCT04544410Lead Sponsor
A Ph2b to Evaluate Tildacerfont in the Reduction of Glucocorticoid Steroid Doses in Adult CAH
PHASE2Terminated
100 participants
Started: Feb 22, 2021 · Completed: Jan 31, 2025
NCT04457336Lead Sponsor
A Ph2b to Evaluate Clinical Efficacy and Safety of Tildacerfont in Adult CAH
PHASE2Terminated
96 participants
Started: Aug 26, 2020 · Completed: May 23, 2024
NCT03687242Lead Sponsor
Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia
PHASE2Completed
11 participants
Started: Sep 6, 2018 · Completed: Aug 9, 2019
Locations (1)
Headquarters
South SF, CA, United States
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