Defunct Company
Total Trials
83
As Lead Sponsor
62
As Collaborator
21
Total Enrollment
14,199
NCT00003780
Chemotherapy Compared to Biological Therapy in Treating Patients With Cancer of the Pancreas
Phase: Phase 2
Role: Lead Sponsor
Start: Dec 31, 1998
Completion: Not specified
NCT00405886
Neramexane for Tinnitus
Start: Oct 31, 2005
Completion: Mar 31, 2007
NCT00429520
Hyaluronic Acid Filler IMD1 Basic for Correction of Nasolabial Folds
Phase: Phase 4
Start: Dec 31, 2005
Completion: Dec 31, 2006
NCT00432666
IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Post-stroke Spasticity of the Upper Limb
Phase: Phase 3
Start: Jun 30, 2006
Completion: May 31, 2008
NCT00407030
IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Cervical Dystonia
Start: Jul 31, 2006
Completion: Jun 30, 2009
NCT00406367
IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Blepharospasm
Start: Oct 31, 2006
Completion: Jul 31, 2009
NCT00430963
IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Glabellar Frown Lines
Completion: Nov 30, 2007
NCT00430586
Finding of Optimal Dose for NT 201 in the Treatment of Glabellar Frown Lines
Start: Nov 30, 2006
Completion: Aug 31, 2007
NCT00465738
IncobotulinumtoxinA (Xeomin) for Upper Limb Spasticity
Start: Feb 28, 2007
NCT00512135
Safety and Efficacy of NT 201 (IncobotulinumtoxinA [Xeomin]) in the Treatment of Glabellar Frown Lines
Start: Jun 18, 2007
Completion: Dec 28, 2009
NCT00507637
Blepharospasm Short Interval
Start: Aug 31, 2007
Completion: Feb 29, 2008
NCT00515944
Evaluate the Migration Potential of Xeomin® Compared to Two Other Botulinum Toxin Type A Products
Phase: Phase 1
Completion: Jun 30, 2008
NCT00541723
Efficacy and Safety of NT 201 in the Treatment of Lateral Periorbital Wrinkles
Start: Sep 30, 2007
NCT00541905
Daily Dystonia Practice - A Trial to Investigate NT 201, the Duration of Treatment Effect After One Injection Session and in Long-term Treatment in Cervical Dystonia
Completion: May 31, 2010
NCT00624026
Memantine - Communication Study
Start: Nov 30, 2007
Completion: Dec 31, 2008
NCT00661440
Efficacy and Safety Study of Neramexane to Treat Congenital and Acquired Nystagmus
Start: May 31, 2008
NCT00694148
Safety and Efficacy of NT 201, Free of Complexing Proteins, in the Treatment of Glabellar Frown Lines
Completion: Jan 31, 2009
NCT00649220
Memantine and Antipsychotics Use
Start: Jul 31, 2008
NCT00712283
Investigate the Effect of Neramexane Mesylate IR Tablet on Driving Fitness and Capability to Operate Machines in Healthy Volunteers
NCT00739635
Efficacy, Safety and Tolerability of Neramexane in Patients With Subjective Tinnitus
Start: Sep 30, 2008
Completion: Feb 28, 2010
NCT00770029
IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Glabellar Frown Lines No. 2
Start: Oct 31, 2008
NCT00770211
NCT00772980
Efficacy, Safety and Tolerability of Neramexane in Comparison to Placebo in Patients With Subjective Tinnitus
Start: Nov 30, 2008
Completion: Jun 30, 2010
NCT00777803
NT 201 (Xeomin®/Bocouture®) in Comparison With Clostridium Botulinum Toxin Type A in the Treatment of Glabellar Frown Lines
Completion: May 31, 2009
NCT00804271
Memantine and Validation of a New Alzheimer's Disease Scale
Start: Dec 31, 2008
Completion: Nov 30, 2009
NCT00827008
Open-Label, Long-Term Treatment Study, to Assess the Long-Term Safety and Tolerability and Efficacy of Neramexane in Patients With Subjective Tinnitus
Start: Jan 31, 2009
Completion: Dec 31, 2011
NCT00872898
Study of Pharmacokinetics, Safety, Efficacy, and Tolerability of Memantine in Children With Autism
Role: Collaborator
Start: Apr 30, 2009
NCT00799942
Open-lable Extension Study on Safety and Efficacy of Neramexane to Treat Congenital and Acquired Nystagmus
Start: May 31, 2009
NCT00915174
Study to Evaluate the Effects of Neramexane on the Pharmacokinetics of a Combined Drospirenone/Ethinyl Estradiol Oral Contraceptive in Healthy Female Subjects
Start: Jun 30, 2009
NCT00936026
Open, Single Center, Three Periods, Fixed Sequence Design Study on the Effects of Clopidogrel Co-administration on the Pharmacokinetics of Neramexane
Start: Jul 31, 2009
Completion: Dec 31, 2009
NCT00955760
Study Analyzing the Effect of Rifampicin Administration on the Pharmacokinetics of Neramexane Mesylate
Start: Aug 31, 2009
NCT00955799
Efficacy, Safety, Tolerability of Neramexane in Patients With Subjective Tinnitus
Start: Sep 30, 2009
Completion: Jun 30, 2011
NCT00978614
Evaluation of Dose-Dependent Repeated-Dose Neramexane Effects on Cardiac Repolarisation (QT/QTc Interval Duration): Electrocardiogram (ECG) Study in Healthy Adult Subjects
Completion: Apr 30, 2010
NCT00983099
Evaluation of Pharmacokinetics, Safety and Tolerability of Single and Multiple Oral Doses of Neramexane Mesylate in Healthy Japanese Subjects
Completion: Sep 30, 2010
NCT00909883
Foot Dystonia Treatment by Botulinum Toxin Injections in Parkinson Disease : Efficiency of Injections Made in Extrinsic Muscle (Flexor Digitorum Longus Muscle) Compared to Intrinsic Muscle (Flexor Digitorum Brevis or Quadratus Plantae Muscles)
Completion: Sep 30, 2012
NCT00972127
Changes in the Renal Excretion of Neramexane by Acidification of Urinary pH Study With and Without Application of a Urinary pH Acidification Regimen
Start: Oct 31, 2009
NCT01999894
Open-label Study of Safety and Tolerability of Memantine in Children With Autism
Start: Nov 30, 2009
Completion: Feb 28, 2013
NCT00773591
Effect of NT 201 (Botulinum Neurotoxin Type A Free of Complexing Proteins) on Sleep-related Breathing Disorders
Start: Mar 31, 2010
Completion: Oct 31, 2010
NCT01109680
A Single Center, Open-Label Study to Quantify Metabolites of [14C]-Neramexane in Plasma and Urine in Healthy Male Subjects
Start: Apr 30, 2010
NCT01098019
Treatment of Notalgia Paresthetica With Xeomin
Completion: Feb 29, 2012
NCT01261741
Investigation of Memantine in the Treatment of Memory, Concentration or Attention Problems
Start: Nov 30, 2010
Completion: Sep 30, 2011
NCT02212119
Safety and Effectiveness of Botulinum Toxin in Elderly Patients With Dementia and Muscle Stiffness
Start: Dec 31, 2010
Completion: Jan 31, 2014
NCT01112371
Contractubex Treatment in Scars After Abdominal Caesarean Section
Start: Feb 28, 2011
NCT01305187
Non-inferiority of Belotero® Basic Versus Juvéderm® Ultra 3
Completion: May 31, 2011
NCT01405482
Botulinum Toxin Injections for Thoracic Outlet Syndrome
Start: Aug 31, 2011
Completion: Jun 30, 2013
NCT01392300
Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Arm After a Stroke
Start: Sep 30, 2011
Completion: Feb 28, 2014
NCT01464307
Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Leg After a Stroke
Start: Dec 31, 2011
Completion: May 31, 2015
NCT01486264
Open-Label Non-Inferiority Study Evaluating the Efficacy and Safety of Xeomin® in Subjects With Cervical Dystonia Flex
Start: Jan 20, 2012
Completion: Mar 29, 2016
NCT01515371
Dose Finding Study for a Botulinum Toxin Type A Injection to Treat Habitual Snoring
Start: Jan 31, 2012
Completion: Nov 30, 2012
NCT01565395
Incobotulinum Toxin A for Sialorrhea in Parkinson's Disease (PD)/Parkinsonism and Amyotrophic Lateral Sclerosis (ALS)
Start: Mar 31, 2012
Completion: Jul 31, 2013
NCT01900041
A Study to Evaluate the Superiority, Efficacy and Tolerability of Combination Pantovigar With 2% Minoxidil vs 2% Minoxidil in Women With Female Pattern Hair Loss
Start: Apr 30, 2012
NCT01603459
Efficacy and Safety Dose Titration Study of Botulinum Toxin Type A to Treat Spasticity in the Leg and Arm
Start: May 31, 2012
Completion: Sep 30, 2014
NCT01686061
Blepharospasm Patient Survey for Patients With Blepharospasm
Phase: N/A
Start: Sep 30, 2012
Completion: Apr 30, 2013
NCT01714960
Safety and Tolerability of MRZ-99030 Eye Drops in Healthy Volunteers and Glaucoma Patients
Start: Oct 31, 2012
Completion: Dec 31, 2013
NCT01893411
Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Leg(s) in Cerebral Palsy
Start: Jun 30, 2013
Completion: May 31, 2016
NCT01905683
Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy
Start: Aug 31, 2013
Completion: Jan 31, 2017
NCT01910896
Effectiveness and Safety Study of Overnight Intensive Patch in Scars
Start: Oct 31, 2013
Completion: Jul 31, 2015
NCT01896895
Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Abnormal Contraction or Twitch of the Eyelid
Start: Nov 30, 2013
Completion: Nov 30, 2016
NCT02002884
Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy
Start: Mar 28, 2014
Completion: Aug 28, 2018
NCT02091739
Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological Conditions
Start: Apr 30, 2014
NCT02188277
Treatment With Xeomin Versus Botox in Children With Spastic Equine and Equinovarus Foot Deformation in Pediatric Cerebral Palsy
Start: Jul 31, 2014
Completion: Dec 31, 2016
NCT02207946
Botulinum Toxin A to Treat Arm Tremor
Start: Dec 5, 2014
Completion: Sep 26, 2016
NCT03119948
Partial Blocks of Rectus Femoris and Soleus With Botulinum Toxin Type A (Xeomin®) to Improve Gait in Hemiparesis
Start: Dec 31, 2014
Completion: Dec 31, 2018
NCT02270736
Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability
Start: Feb 9, 2015
Completion: May 7, 2019
NCT02462317
Study of the Effects on Motor Recovery of Early Post-stroke Spasticity Treatment
Start: Apr 30, 2015
Completion: Dec 9, 2020
NCT02577224
An RCT of a Patient-initiated Treatment Service for BEB and HFS
Start: Aug 31, 2015
Completion: Feb 28, 2018
NCT04210258
Post-Market Clinical Follow-up Performance and Safety Study of Etermis 3 and 4 in the Face
Start: Jun 1, 2016
Completion: Dec 27, 2017
NCT03256942
Evaluation of the Sensitivity of Merz Lips Fullness Assessment Scale Following Etermis 4® Treatment for Lips Volume Augmentation
Start: Aug 16, 2017
Completion: Nov 17, 2017
NCT03986424
Local Study of Akatinol Memantine in VaD in Russia
Start: Jan 23, 2018
Completion: Jun 1, 2022
NCT03650387
Safety, Effectiveness and Participant Satisfaction Study of a Dermal Filler (of RADIESSE® (+) Lidocaine) in the Treatment of Ageing Signs in the Face
Start: Sep 17, 2018
Completion: May 26, 2020
NCT03806933
Study to Investigate the Safety and Duration of Effect of Different Botulinum Toxin A (NT 201) Dose Groups Following the Treatment of Glabellar Frown Lines
Start: Jan 23, 2019
Completion: Oct 8, 2020
NCT03992404
Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury
Start: Sep 16, 2019
Completion: Apr 30, 2027
NCT04075981
Prevention Atrial Fibrillation by BOTulinum Toxin Injections (BOTAF)
Start: Sep 30, 2019
Completion: Sep 30, 2026
NCT04177212
Investigation of the Effectiveness and Safety of MRZF111 in the Treatment of Décolleté Wrinkles
Start: Dec 4, 2019
Completion: Feb 23, 2021
NCT04594213
Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Lateral Canthal Lines) in Subjects With Moderate to Severe Upper Facial Lines
Start: Sep 23, 2020
Completion: May 9, 2022
NCT04622254
Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Crows Feet) in Subjects With Moderate to Severe Upper Facial Lines
Start: Nov 12, 2020
Completion: Jul 8, 2022
NCT04766723
A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm
Start: Feb 24, 2021
Completion: Nov 20, 2023
NCT04792398
Bruxism Xeomin® Intervention Trial
Start: May 1, 2021
Completion: Jun 30, 2023
NCT04908423
Xeomin® and Gait Related Mobility After Stroke
Start: Oct 19, 2021
Completion: Apr 30, 2026
NCT05585398
A Study to Evaluate the Distribution of Botulinum Neurotoxin Type A Administered as Intradermal Injections, Comparing Different Doses, Concentrations, and Delivery Methods
Start: Oct 19, 2022
Completion: Apr 13, 2023
NCT05327972
DEgenerative ROtator Cuff Disease and Botulinum TOXin
Start: Jan 20, 2023
Completion: Feb 28, 2027
NCT05623111
Perineural Injections of Incobotulinumtoxin-A for Diabetic Neuropathic Pain of the Lower Extremities
Start: Aug 1, 2023
Completion: Feb 1, 2026
NCT06995287
Evaluation of the Analgesic Effect of Intramyometrial Botulinum Toxin Injection Via Hysteroscopy in Severe Primary Dysmenorrhea
Start: Jun 1, 2025
Completion: Jan 1, 2028