About
Small Molecule Combination
Areas of Focus
Categories
Small Molecule Pharmaceutical
Clinical Trials (11)
View allTotal Trials
11
As Lead Sponsor
10
As Collaborator
1
Total Enrollment
367
By Phase
PHASE1/PHASE2: 4PHASE2: 4PHASE1: 3
By Status
COMPLETED: 6WITHDRAWN: 2RECRUITING: 1TERMINATED: 1ACTIVE_NOT_RECRUITING: 1
Clinical Trials Pipeline11 trials
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Phase 1/2
Phase 2/3
N/A
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027
Today
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Recent Trials
NCT05588648Lead Sponsor
Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma
PHASE1/PHASE2Recruiting
48 participants
Started: May 1, 2023 · Completed: Dec 31, 2025
NCT06219733Lead Sponsor
Vactosertib and Imatinib Combination in Patients with Advanced Desmoid Tumor/aggressive Fibromatosis (DT/AF)
PHASE2Withdrawn
Started: Jun 1, 2021 · Completed: May 23, 2022
NCT04515979Lead Sponsor
Vactosertib in Combination with Pembrolizumab for PD-L1 Positive Non-small Cell Lung Cancer (NSCLC) Subjects
PHASE2Terminated
11 participants
Started: Dec 17, 2020 · Completed: Aug 5, 2024
NCT04064190Lead Sponsor
Vactosertib with Durvalumab in Urothelial Carcinoma Failing Checkpoint Inhibition
PHASE2Withdrawn
Started: Dec 13, 2019 · Completed: Dec 30, 2024
NCT03844750Collaborator
Preoperative Immunotherapy (Pembrolizumab) for Patients With Colorectal Cancer and Resectable Hepatic Metastases
PHASE2Active, not recruiting
6 participants
Started: Jul 22, 2019 · Completed: Apr 30, 2026
Locations (1)
Headquarters
Seoul, Korea
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