Defunct Company
Total Trials
17
As Lead Sponsor
As Collaborator
0
Total Enrollment
1,350
NCT01921426
A Phase 1 Dose Escalation Study of GC4419 in Combination With Chemoradiation for Squamous Cell Cancer of the Head & Neck
Phase: Phase 1
Role: Lead Sponsor
Start: Aug 31, 2013
Completion: Aug 31, 2016
NCT02508389
A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer
Phase: Phase 2
Start: Oct 12, 2015
Completion: Aug 29, 2019
NCT03096756
A Study of the Safety, Tolerability and Pharmacokinetics of Orally-administered GC4702 in Healthy Volunteers
Start: Jul 26, 2016
Completion: Dec 31, 2016
NCT03163173
A Study to Investigate the Absorption, Metabolism, Excretion, and Mass Balance of GC4419 in Healthy Adult Subjects
Start: Aug 14, 2017
Completion: Oct 13, 2017
NCT03164109
A Phase 1, Randomized, Placebo-and Positive-Controlled Crossover Study to Determine the Effect of Single-Dose GC4419 on QTc Interval in Healthy Volunteers
Start: Aug 18, 2017
NCT03194139
A Study Designed to Compare the Safety and Pharmacokinetics of Intravenously Administered Superoxide Dismutase Mimetic GC4711 and GC4419 in Healthy Volunteers
Start: Sep 25, 2017
Completion: Dec 24, 2017
NCT03340974
Pilot Dose Escalation Trial of Stereotactic Body Radiation Therapy (SBRT) in Combination With GC4419 in Pancreatic Cancer
Phase: Phase 1/2
Start: Feb 12, 2018
Completion: May 26, 2021
NCT03689712
ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer Patients
Phase: Phase 3
Start: Oct 3, 2018
Completion: Aug 25, 2023
NCT03099824
A Phase 1 Study of the Safety and Pharmacokinetics of GC4711 (Oral Capsule) Compared to GC4419 (IV Infusion) and GC4711 (IV Infusion) in Healthy Volunteers
Start: Oct 16, 2018
Completion: Jan 27, 2020
NCT03792971
Study to Evaluate the Effects of 90 mg Intravenous Infusions of GC4419 on the Single Dose Pharmacokinetics of Dextromethorphan in Healthy Adult Subjects
Start: Feb 10, 2019
Completion: Feb 15, 2019
NCT03762031
A Study Designed to Evaluate the Safety and Pharmacokinetics of Intravenously Administered Superoxide Dismutase Mimetic GC4711 in Healthy Volunteers
Start: Mar 19, 2019
Completion: Mar 4, 2020
NCT05412472
Study to Evaluate the Effects of Renal Impairment on the Pharmacokinetics, Safety and Tolerability of GC4419
Start: Apr 4, 2019
Completion: Apr 6, 2021
NCT04225026
Effects of Intravenous GC4419 on the Incidence and Severity of Esophagitis Due to Chemoradiotherapy for Lung Cancer
Start: Dec 19, 2019
Completion: Mar 27, 2022
NCT04529850
Ph 2 Open Label Study of GC4419 to Reduce SOM Associated With Chemoradiotherapy for Head and Neck Cancer
Start: Jun 30, 2020
Completion: Mar 10, 2021
NCT04555096
A Trial of GC4419 in Patients With Critical Illness Due to COVID-19
Start: Sep 9, 2020
Completion: May 28, 2021
NCT04476797
Phase I/II Study of SBRT and GC4711 for Centrally Located or Large NSCLC
Start: Oct 18, 2020
Completion: Nov 28, 2023
NCT04698915
Phase 2b Study of GC4711 in Combination With SBRT for Nonmetastatic Pancreatic Cancer
Start: May 7, 2021
Completion: Nov 30, 2023