Small Molecules
Total Trials
17
As Lead Sponsor
As Collaborator
0
Total Enrollment
1,363
NCT03276858
Single and Multiple-Ascending Dose Study of CRN00808 in Healthy Volunteers
Phase: Phase 1
Role: Lead Sponsor
Start: Sep 22, 2017
Completion: Apr 30, 2018
NCT04261712
A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)
Phase: Phase 2
Start: Jan 29, 2019
Completion: Mar 31, 2028
NCT03792555
A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Evolve)
Start: Mar 11, 2019
Completion: Aug 12, 2020
NCT03789656
An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge)
Start: Mar 12, 2019
Completion: Aug 31, 2020
NCT03936166
A Single and Multiple-Ascending Dose Study of CRN01941 in Healthy Adult Volunteers
Start: Apr 29, 2019
Completion: Dec 16, 2019
NCT04246749
Mass Balance and Pharmacokinetics of [14C]-CRN00808 in Healthy Volunteers
Start: Sep 17, 2019
Completion: Oct 25, 2019
NCT06048887
Single and Multiple-Ascending Dose Study of CRN04894 in Healthy Volunteers
Start: Dec 18, 2020
Completion: Apr 11, 2022
NCT04837040
A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly
Phase: Phase 3
Start: May 12, 2021
Completion: Jun 30, 2027
NCT05192382
A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2)
Start: Dec 17, 2021
Completion: Jan 31, 2028
NCT05361668
Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid Syndrome
Start: Jun 17, 2022
Completion: Feb 28, 2026
NCT05907291
Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)
Start: Jul 3, 2023
Completion: Aug 22, 2025
NCT05804669
A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome
Phase: Phase 1/2
Start: Oct 12, 2023
Completion: Oct 31, 2026
NCT06712823
An Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894
Start: Feb 25, 2025
Completion: Nov 30, 2027
NCT07144163
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
Start: Sep 30, 2025
Completion: May 31, 2027
NCT07159841
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
Phase: Phase 2/3
Completion: Mar 31, 2030
NCT07087054
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
Start: Oct 31, 2025
Completion: Jan 31, 2030
NCT07129252
A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors
Completion: Aug 31, 2029
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