Umbrella company acquiring drug companies
Total Trials
14
As Lead Sponsor
4
As Collaborator
10
Total Enrollment
789
NCT04073498
The Safety and Tolerability of SerpinPC in Healthy Men and in Men with Severe Blood Disorders (haemophilia a and B)
Phase: Phase 1/2
Role: Collaborator
Start: Aug 14, 2019
Completion: Sep 26, 2024
NCT04443192
A Single Ascending and Repeated Dose Study of Oral ZF874 in Healthy Volunteers and PiXZ Subjects
Phase: Phase 1
Start: Aug 3, 2020
Completion: Sep 12, 2022
NCT04152837
Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease
Phase: Phase 3
Start: Sep 2, 2020
Completion: Jul 29, 2022
NCT04064346
Efficacy and Safety of Lixivaptan in the Treatment of Autosomal Dominant Polycystic Kidney Disease
Start: Oct 28, 2021
Completion: Aug 3, 2022
NCT05208866
Roll-over Study to Assess Safety of Lixivaptan in Participants With ADPKD Who Completed Study PA-ADPKD-303
Start: Feb 10, 2022
NCT05323110
Study of Intravenously Administered Anti-LIGHT Monoclonal Antibody CBS001 in Healthy Volunteers
Start: Apr 14, 2022
Completion: Aug 22, 2023
NCT05605678
Hemophilia Non-Interventional Study Prior to SerpinPC Intervention (PRESent-5)
Phase: N/A
Start: Dec 9, 2022
Completion: Nov 29, 2024
NCT05821777
A Study to Evaluate Safety, Tolerability and Preliminary Activity of LB101 in Participants With Advanced Solid Tumors
Role: Lead Sponsor
Start: Mar 28, 2023
Completion: Sep 9, 2025
NCT05789524
The Efficacy and Safety of SerpinPC in Participants with Severe Hemophilia a or Moderately Severe to Severe Hemophilia B
Phase: Phase 2
Start: Jul 6, 2023
Completion: Feb 28, 2025
NCT05789537
A Study of SerpinPC in Participants with Hemophilia B (HemB) with Inhibitors
Start: Jul 28, 2023
Completion: Feb 24, 2025
NCT06568302
The Long-term Safety and Efficacy of SerpinPC in Subjects with Hemophilia Who Completed a Sponsored SerpinPC Clinical Trial
Start: Jul 11, 2024
Completion: Jan 29, 2025
NCT06752668
A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
Start: Dec 23, 2024
Completion: Dec 31, 2025
NCT07082829
A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age
Start: Jun 30, 2025
NCT07096674
A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
Start: Aug 12, 2025
Completion: Apr 30, 2026
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