Small Molecules, Injector
Total Trials
30
As Lead Sponsor
29
As Collaborator
1
Total Enrollment
3,260
NCT00642928
Dose Range Finding Study of BF2.649 Versus Placebo to Treat Excessive Daytime Sleepiness in Parkinson's Disease Patients
Phase: Phase 2
Role: Lead Sponsor
Start: Oct 31, 2007
Completion: Jun 30, 2009
NCT00690274
Study to Demonstrate Cognitive Enhancing Effects of BF2.649
Role: Collaborator
Start: Jun 30, 2008
Completion: Oct 31, 2011
NCT01067222
Efficacy and Safety Study of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy
Phase: Phase 3
Start: May 31, 2009
Completion: Dec 31, 2010
NCT01067235
Efficacy and Safety Study of BF2.649 and BF2.649 Add on Modafinil on Cataplexy in Patients With Narcolespy
Start: Oct 31, 2009
Completion: Jul 31, 2010
NCT01036139
Efficacy and Safety of BF2.649 in Excessive Daytime Sleepiness (EDS) in Parkinson's Disease
Start: Dec 31, 2009
Completion: Aug 31, 2012
NCT01066442
Start: Mar 31, 2010
NCT01620554
Dose-range Finding Study of BF2.649 Effect on Patients With Obstructive Sleep Apnea (OSA)
Start: Oct 31, 2010
Completion: Dec 31, 2011
NCT01638403
Effects of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy.
Start: Nov 30, 2010
Completion: Jul 31, 2012
NCT01399606
Long Term Open Label Study in Narcolepsy With BF2.649 (Pitolisant)
Start: May 31, 2011
Completion: Sep 30, 2016
NCT01619033
Pharmacokinetics of BF2.649 in Renal Impairment
Phase: Phase 1
Start: Jul 31, 2011
Completion: Nov 30, 2012
NCT01071876
BF2.649 in Patients With OSA and Treated by CPAP But Still Complaining of EDS
Start: Aug 31, 2011
Completion: Mar 31, 2014
NCT01072968
BF2.649 in Patients With OSA, Still Complaining of EDS and Refusing to be Treated by CPAP.
Start: Oct 31, 2011
Completion: May 31, 2014
NCT01789398
Patient Narcoleptic Treated With BF2.649 (Pitolisant) in add-on to Sodium Oxybate (HARMONY IV)
Start: Sep 30, 2012
Completion: Aug 31, 2014
NCT01785147
Efficacy and Safety of BP1.4979 in Smoking Cessation
Start: Feb 28, 2013
Completion: Oct 31, 2014
NCT01800045
Pitolisant to Assess Weekly Frequency of Cataplexy Attacks and EDS in Narcoleptic Patients (HARMONY CTP)
Start: Apr 30, 2013
Completion: Jan 31, 2015
NCT01948011
Racecadotril Suspension Linearity Study & Comparative Bioavailability Versus Granules
Start: Sep 30, 2013
Completion: Nov 30, 2013
NCT01965301
First-time-in-man, to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BP1.5375
Start: Oct 31, 2014
Completion: Dec 31, 2014
NCT02739568
Pitolisant (BF2.649) in the Treatment of EDS in Patients With OSA
Start: Apr 30, 2016
Completion: Apr 30, 2020
NCT02611687
Efficacy and Safety of Pitolisant in Pediatric Narcoleptic Patients With or Without Cataplexy, Double-blind Study Followed by a Prolonged Open-label Period
Start: Jun 6, 2016
Completion: Jun 5, 2025
NCT02929342
Study to Assess the Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]-Pitolisant in Healthy Male Volunteers
Start: Jul 31, 2016
Completion: Aug 31, 2016
NCT02800083
A Trial Evaluating Pitolisant (BF2.649) in Alcohol Use Disorder Treatment
Start: Oct 31, 2016
Completion: Not specified
NCT03152123
Determination the Abuse Potential of Pitolisant in Healthy, Non-Dependent Recreational Stimulant Users
Start: Mar 15, 2017
Completion: Oct 23, 2017
NCT03424824
Randomized Clinical Trial Evaluating BP1.3656 Versus Placebo For Alcohol Use Disorder Treatment
Start: Jan 9, 2018
Completion: Nov 24, 2021
NCT03345953
Clinical Trial Assessing the Efficacy and Safety of BP1.4979 in Restless Legs Syndrome
Start: Feb 6, 2018
Completion: Apr 29, 2020
NCT05118906
Pilot Study on BP1.4979 Effect on Binge Eating Disorders
Start: Mar 7, 2022
Completion: Sep 30, 2025
NCT05240560
Proof of Concept Study Evaluating BP1.3656 in Patients With Fatigue Following Ischemic Stroke
Start: Jan 20, 2023
Completion: Feb 8, 2024
NCT05953389
Proof of Concept Study on Pitolisant Effect on Autism Spectrum Disorders in Children and Adolescents
Start: Dec 20, 2023
Completion: Nov 30, 2025
NCT07074002
Proof of Concept Study on BP1.4979 Effect on Essential Tremor
Start: Jul 31, 2025
Completion: Dec 31, 2026
NCT07047404
Proof of Concept Study on BP1.4979 Effect on Primary Premature Ejaculation
Start: Sep 15, 2025
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