Therapies for hepatologic diseases and viral infections
Total Trials
13
As Lead Sponsor
As Collaborator
0
Total Enrollment
929
NCT04485663
A Study of ALG-010133 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects
Phase: Phase 1
Role: Lead Sponsor
Start: Aug 17, 2020
Completion: Mar 8, 2022
NCT04536337
A Study of ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects
Start: Oct 22, 2020
Completion: Jun 16, 2025
NCT05001022
A Study of ALG-020572 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single Doses in Healthy Volunteers and Multiple Doses in CHB Subjects
Start: Sep 25, 2021
Completion: Jul 18, 2022
NCT05090111
A Study of ALG-055009 in Healthy Volunteers and Subjects With Hyperlipidemia
Start: Dec 1, 2021
Completion: Jun 16, 2023
NCT05561530
A Study of ALG-125755 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics After Single Doses in Healthy Volunteers, and Single and Multiple Doses in CHB Subjects
Start: Oct 7, 2022
Completion: Jun 15, 2023
NCT05840952
A First-in-Human Multi-Part Phase 1 Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558
Start: Jul 4, 2023
Completion: Apr 29, 2024
NCT06191991
A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)
Start: Nov 3, 2023
Completion: Dec 4, 2023
NCT06342947
ALG-055009 in Non-cirrhotic Adults With MASH (HERALD)
Phase: Phase 2
Start: Apr 1, 2024
Completion: Sep 9, 2024
NCT06672900
A Multi-part Study of ALG-000184 to Evaluate Safety, Tolerability, Pharmacokinetics and Drug-drug Interaction Potential After Single and Multiple Doses in Healthy Volunteers
Start: Jan 9, 2025
Completion: Jul 7, 2025
NCT06568861
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ALG-097558 in Subjects With Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function
Start: Jan 14, 2025
Completion: Jul 28, 2025
NCT06698549
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ALG-097558 in Subjects With Renal Impairment and in Healthy Subjects With Normal Renal Function
Start: Feb 1, 2025
Completion: Jul 21, 2025
NCT06959888
A Phase 1 Study in Healthy Volunteers to Evaluate the Relative Bioavailability of ALG-055009 Formulations
Start: Mar 25, 2025
Completion: May 16, 2025
NCT06963710
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)
Start: Jul 15, 2025
Completion: Aug 31, 2028
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