Alzheimer's Antibody Treatments
Total Trials
12
As Lead Sponsor
10
As Collaborator
2
Total Enrollment
1,701
NCT03636204
A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) Mutation
Phase: Phase 1
Role: Lead Sponsor
Start: Sep 14, 2018
Completion: Dec 31, 2019
NCT03635047
A Phase I Study for Safety and Tolerability of AL002.
Start: Nov 12, 2018
Completion: Nov 25, 2020
NCT03822208
First in Human Study for Safety and Tolerability of AL003.
Start: Mar 29, 2019
Completion: May 6, 2021
NCT03987295
A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)
Phase: Phase 2
Start: Sep 27, 2019
Completion: Jun 5, 2024
NCT04111666
A Phase 1 First in Human Study to Assess Safety and Tolerability of AL101
Start: Dec 14, 2019
Completion: Jun 9, 2022
NCT04374136
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)
Phase: Phase 3
Start: Jul 23, 2020
Completion: Aug 3, 2027
NCT04592874
A Phase 2 Study to Evaluate Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease
Start: Jan 22, 2021
Completion: Sep 12, 2024
NCT05053035
A Phase 2 Study to Evaluate AL001 in C9orf72-Associated ALS
Start: Sep 2, 2021
Completion: Oct 28, 2022
NCT05744401
A Long-term Extension Study to Evaluate Safety, Tolerability, and Efficacy of AL002 in Alzheimer's Disease
Start: Jan 4, 2023
Completion: Jan 31, 2025
NCT06079190
Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease
Role: Collaborator
Start: Oct 20, 2023
Completion: Nov 23, 2026
NCT06111014
Continuation Study for Latozinemab
Start: Dec 8, 2023
Completion: Nov 30, 2027
NCT07105709
Open-label Extension Study in Participants With Early Alzheimer's Disease
Start: Aug 14, 2025
Completion: Nov 24, 2028
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