Defunct Company
Total Trials
20
As Lead Sponsor
18
As Collaborator
2
Total Enrollment
1,629,950
NCT02778646
Detection of Familial Hypercholesterolaemia in Cardiovascular Disease Registry
Phase: N/A
Role: Collaborator
Start: Jan 31, 2003
Completion: Dec 31, 2014
NCT01556906
Safety, Tolerability and Efficacy of Microsomal Triglyceride Protein (MTP) Inhibitor
Phase: Phase 2
Role: Lead Sponsor
Start: Jun 30, 2003
Completion: Feb 29, 2004
NCT00359281
Pharmacokinetic Drug Interactions of AEGR-733 on Lipid-lowering Agents
Start: Mar 31, 2006
Completion: Nov 30, 2007
NCT00405067
The Safety & Efficacy of Combination BMS-201038 (AEGR-733) & Ezetimibe vs. Monotherapy in Moderate Hypercholesterolemia
Start: May 31, 2006
Completion: Jan 31, 2007
NCT00474240
AEGR-733 and Atorvastatin 20 mg vs. Monotherapy in Moderate Hypercholesterolemia
Start: Apr 30, 2007
Completion: Oct 31, 2008
NCT00559962
Evaluate Low Doses of AEGR-733 on Hepatic Fat Accumulation by MRS
Start: Oct 31, 2007
Completion: Nov 30, 2008
NCT00730236
A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)
Phase: Phase 3
Start: Dec 31, 2007
Completion: Oct 31, 2011
NCT00690443
Evaluate Safety and Efficacy of AEGR-733 and Atorvastatin vs Atorvastatin Monotherapy in Hypercholesterolemia
Start: May 31, 2008
Completion: Sep 30, 2008
NCT00943306
Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia
Start: Oct 29, 2009
Completion: Dec 1, 2014
NCT01760187
Phase I Study of the Safety, Tolerability, PK & PD of Lomitapide in Japanese and Caucasian Subjects With Elevated LDL-C
Phase: Phase 1
Start: Nov 7, 2012
Completion: Jun 3, 2013
NCT01915771
Study to Determine the Intra-subject Variability of Pharmacokinetics of Lomitapide in Healthy Subjects
Start: Jul 29, 2013
Completion: Aug 23, 2013
NCT02044419
A Comparative Bioavailability Study of Lomitapide 20 mg Intact vs Sprinkled
Start: Oct 30, 2013
Completion: Dec 23, 2013
NCT02009345
Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada
Start: Nov 30, 2013
Completion: Nov 30, 2028
NCT02080455
Evaluate the Effect of Atorvastatin on the Pharmacokinetics of Lomitapide in Healthy Subjects.
Start: Jan 27, 2014
Completion: Mar 7, 2014
NCT02080468
Evaluate the Effect of Ethinyl Estradiol/Norgestimate on the Pharmacokinetics of Lomitapide in Healthy Female Subjects
Start: Feb 19, 2014
Completion: Apr 24, 2014
NCT02173158
Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering Therapy
Start: Apr 2, 2014
Completion: Dec 17, 2015
NCT02399852
Effects of Lomitapide on Carotid and Aortic Atherosclerosis
Start: Jun 30, 2015
Completion: Dec 31, 2021
NCT02765841
Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering Therapy
Start: May 31, 2016
Completion: Dec 31, 2019
NCT02325674
MEASuRE: Metreleptin Effectiveness And Safety Registry
Start: Oct 11, 2016
Completion: Oct 31, 2031
NCT04026178
Immunogenicity of Metreleptin in Patients With Generalized Lipodystrophy
Phase: Phase 4
Start: Nov 14, 2018
Completion: Apr 30, 2025