Adeno-Associated Virus Delivery, Gene Therapy
Total Trials
10
As Lead Sponsor
9
As Collaborator
1
Total Enrollment
556
NCT01494805
Safety and Efficacy Study of rAAV.sFlt-1 in Patients With Exudative Age-Related Macular Degeneration
Phase: Phase 1/2
Role: Collaborator
Start: Dec 31, 2011
Completion: Aug 31, 2017
NCT02840669
A Study to Characterize the Cardiac Phenotype of Individuals With Friedreich's Ataxia (CARFA Study)
Phase: N/A
Role: Lead Sponsor
Start: Jul 31, 2016
Completion: Sep 30, 2018
NCT02168686
Safety Dose Finding Study of ADVM-043 Gene Therapy to Treat Alpha-1 Antitrypsin (A1AT) Deficiency
Start: Nov 28, 2017
Completion: Aug 29, 2019
NCT03748784
ADVM-022 Intravitreal Gene Therapy for Wet AMD
Phase: Phase 1
Start: Nov 14, 2018
Completion: Jun 22, 2022
NCT03804021
Long-Term Follow-up Study of ADVM-043
Start: Dec 27, 2018
Completion: Dec 6, 2021
NCT04418427
ADVM-022 Intravitreal Gene Therapy for DME
Phase: Phase 2
Start: May 28, 2020
Completion: Jun 14, 2023
NCT04645212
Long-term Study of ADVM-022 in Neovascular (Wet) AMD [OPTIC-EXT]
Start: Dec 14, 2020
Completion: Jun 30, 2025
NCT05607810
Long-Term Follow-up Study of ADVM-022 in DME (INFINITY-EXT)
Start: Aug 10, 2022
Completion: Apr 30, 2026
NCT05536973
Safety and Efficacy of ADVM-022 in Treatment-Experienced Patients With Neovascular Age-related Macular Degeneration [LUNA]
Start: Aug 23, 2022
Completion: Aug 31, 2028
NCT06856577
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration
Phase: Phase 3
Start: Feb 28, 2025
Completion: Mar 25, 2030
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